Vaktam

Brand Name: Vaktam 1.5 gm (Injection)

Composition: Ceftriaxone 1000 mg & Sulbactam 500 mg 

Marketed By: Butame Pharma Pvt Ltd

MRP: Rs 185 per vial

About Vaktam

Vaktam is a combination antibiotic injection containing 1000 mg of Ceftriaxone and 500 mg of Sulbactam. Ceftriaxone is a broad-spectrum cephalosporin antibiotic that works by inhibiting the synthesis of bacterial cell walls, leading to cell death. Sulbactam is a beta-lactamase inhibitor that enhances the efficacy of Ceftriaxone by preventing bacterial resistance mechanisms. Together, they provide a potent treatment for a variety of bacterial infections.

Uses and Benefits

Vaktam is indicated for the treatment of a wide range of bacterial infections, including but not limited to:

• Respiratory Tract Infections: Effective against infections such as pneumonia and bronchitis.
• Urinary Tract Infections: Treats complex and uncomplicated urinary tract infections.
• Intra-abdominal Infections: Useful for peritonitis and other abdominal infections.
• Skin and Soft Tissue Infections: Addresses cellulitis, abscesses, and wound infections.
• Bone and Joint Infections: Treats osteomyelitis and septic arthritis.
• Gynecological Infections: Effective against pelvic inflammatory disease.
• Septicemia: Manages severe bloodstream infections.
• Meningitis: Used for bacterial infections of the meninges.

The combination of Ceftriaxone and Sulbactam in Vaktam provides an enhanced antibacterial effect, particularly against beta-lactamase-producing bacteria, offering a broader spectrum of activity and reducing the risk of antibiotic resistance.

Side Effects

While Vaktam is effective in treating bacterial infections, it may cause some side effects, including:

• Common Side Effects:
  • Pain or inflammation at the injection site
  • Diarrhea
  • Nausea or vomiting
  • Rash or itching
• Serious Side Effects:
  • Severe allergic reactions (anaphylaxis), including swelling of the face, lips, tongue, or throat
  • Clostridium difficile-associated diarrhea
  • Hematologic changes such as thrombocytopenia, leukopenia
  • Hepatic dysfunction including elevated liver enzymes
  • Renal impairment

If any severe side effects occur, it is crucial to seek immediate medical attention.

How to Use

• Administration: Vaktam should be administered by a healthcare professional. It is given as an intravenous (IV) or intramuscular (IM) injection, depending on the specific medical condition and patient needs.
• Dosage: The dosage and duration of treatment depend on the type and severity of the infection, as well as the patient’s age, weight, and overall health. Follow the doctor’s instructions precisely.
• Preparation: Healthcare providers will prepare the injection according to medical standards, ensuring the correct dosage and sterile conditions.
• Monitoring: Patients may be monitored during and after administration to observe for any adverse reactions or side effects.

Safety Advice

• Medical History: Inform your healthcare provider about your complete medical history, especially any kidney or liver disease, gallbladder disease, or gastrointestinal conditions such as colitis.
• Allergies: Disclose any known allergies to Ceftriaxone, Sulbactam, other antibiotics, or any other medications.
• Drug Interactions: Certain drugs can interact with Vaktam, including other antibiotics, anticoagulants, and calcium-containing IV solutions. Provide a complete list of current medications to your healthcare provider.
• Pregnancy and Breastfeeding: Discuss the risks and benefits with your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
• Renal and Hepatic Function: Regular monitoring of kidney and liver function may be required during prolonged therapy.
• Use in Infants: Ceftriaxone can displace bilirubin from serum albumin, potentially leading to bilirubin encephalopathy in neonates. Caution is advised when used in this population.
• Overdose: In case of suspected overdose, immediate medical intervention is required.

Vaktam offers a robust solution for managing a variety of serious bacterial infections through its combination of Ceftriaxone and Sulbactam. Proper use and adherence to medical advice are essential to maximize its benefits and minimize potential risks. Always follow the guidance of healthcare professionals when using this medication.